Abnormal Hyperactivation in the Brain May Be an Early Sign of Alzheimer’s

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Summary: Hyperactivation in specific brain areas may be an early biomarker for Alzheimer’s disease. Researchers found those who reported concerns over diminished memory skills, and with...

New Position Statement on the Importance of Sleep to Health and Well-Being

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An American Academy of Sleep Medicine position statement published in the Journal of Clinical Sleep Medicine focused on the importance of sleep to health and provided...

Galcanezumab Reduces Migraine Days and Disabling Nonpain Symptoms

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Galcanezumab, a calcitonin gene-related peptide (CGRP) monoclonal antibody, is associated with a reduction in the frequency of migraine headache days and a reduction in potentially disabling...

Sedation drug shows promise for neurological benefits after subarachnoid hemorrhage » McKnight Brain Institute...

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(From left) Drs. Sylvain Doré and Katharina Busl By Michelle Koidin Jaffee A drug widely used for anesthesia and sedation in patients...

Research Does Not Support the Adage “Boys Will Be Boys”

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Summary: Study reveals there are not that many “girlish girls” or “boyish boys.”Source: University of HelsinkiA research article published in the European Journal of Personality demonstrates that girls...

How to Nurture Creativity in Your Kids

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Summary: Researches investigate the positive impact of nurturing creativity in children and evaluate methods for encouraging creativity.Source: UConnParents who want their kids to be more creative...

Light Smokers May Not Escape Nicotine Addiction

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Summary: Those who consider themselves to be light smokers, in that they smoke between one to four cigarettes a day, meet the criteria for nicotine addiction.Source:...

Protein Linked to Sex Differences in Age-Related Dopamine Neuron Loss

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Summary: The VGLUT protein is more abundant in the dopamine neurons of female fruit flies, rodents, and humans than in males. The finding shed light on...

Q&A: Outgoing ASET President Connie Kubiak Shares Experiences and Advice

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This summer, Connie Kubiak will have completed one of the most trying presidencies at ASET-The Neurodiagnostic Society.But through it all, Kubiak has remained committed to serving...

Myelin Loss Is a Major Factor in Age-Related Brain Deterioration

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Summary: Cells that drive myelin repair become less efficient due to aging. Myelin loss results in cognitive decline and is central to a number of neurodegenerative...

UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel...

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The University of Florida and UF Health on Tuesday announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving...

Preterm Exposure to Corticosteroids and Risk for Mental or Behavioral Disorders

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Exposure to antenatal corticosteroids is associated with a reduced risk for neurodevelopmental impairment in children with extremely preterm birth but an increased risk for adverse neurocognitive...

Covid 19: Analysis and Recommendations for Prevention and Treatment

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The recommendations below are a compilation of Dr. Izor and NSC staff, as well as adapted from Paul Marik, MD’s MATH+ protocol....

Evobrutinib Reduces Slowly Expanding Lesion Volume in Relapsing Multiple Sclerosis

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The following article is part of conference coverage from the 2022 American Academy of Neurology (AAN) Annual Meeting. Neurology Advisor’s staff will be reporting breaking news...

Have You Fallen for the Myth of ‘I Can’t Draw’? Do It Anyway –...

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Summary: Researchers say whether you are a competent artist or not, drawing and doodling can have a positive effect on your mental health and can help...

No Overall Benefit of Early Anticoagulant Therapy for Ischemic Stroke

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Early use of anticoagulants has no overall beneficial effect for patients with acute ischemic stroke, as an update of a Cochrane Review published in Cochrane Database...

Kappa-Free Light Chain Index Predicts Early Multiple Sclerosis Disease Activity

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A high κ-free light chain (κ-FLC) index may predict early disease activity in multiple sclerosis (MS) and, compared to determination of cerebrospinal fluid (CSF)-restricted oligoclonal band...

Study Calls for Change in Guidance About Eating Fish During Pregnancy

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Summary: Essential nutrients found in fish counteract and provide neuroprotection against mercury in fish, researchers report. The new study says eating fish during pregnancy can help...

Speech Droplets Drive Transmission of COVID-19

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Summary: Speaking without a facemask in confined spaces poses the biggest risk for spreading SARS_CoV_2, the virus responsible for COVID-19.Source: WileyA new review published in the Journal...

Why Our Movement Disorders Specialists Love Botulinum

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When you hear the word Botox, we know what you’re thinking. In the public...

Sleep-Deprived Youth at Risk for Depression, Cognitive Problems

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Preteens who don’t get the recommended 9 hours of sleep...

Unique Physical Therapy Method Sidesteps Fatigue for MS Patients

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Physical therapists are employing a unique method of exercise addressing fatigue that multiple sclerosis (MS) patients often encounter.In fact, the use of blood-flow restriction training (BFRT)...

Expert Consensus Statement: Determining Brain Death/Death by Neurologic Criteria

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Experts in brain death/death by neurologic criteria (BD/DNC) have convened to publish a consensus statement on global recommendations for determining brain death/death (BD/DNC) by neurologic criteria,...

FDA Authorizes COVID-19 Test That Provides Rapid Results at Home

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The Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to Lucira Health for its at-home molecular test intended to detect severe acute...

next steps » Department of Neurology » College of Medicine » University of Florida

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Congratulations to Drs. Joshua Wong and Michael Okun on the publication of “Connectomic imaging to predict and prevent cognitive decline after subthalamic DBS: next steps,” in...

Lifetime of Knowledge Can Clutter Memories of Older Adults

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Summary: Older people’s brains allocate more space to accumulated knowledge and have more material to navigate when trying to access memories, a new study reports.Source: Cell...

Brain Stimulation Could Help You Decide When to Give Up

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Summary: Repetitive transcranial magnetic stimulation (rTMS) can be used to modulate brain rhythms and cognitive behaviors related to “giving up” during problem-solving tasks.Source: University of TsukubaNew...

Two Keys to Boosting Employee Satisfaction

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With employees outnumbering job openings, turnover in healthcare is high. This can be costly for practices and disruptive to patients. Practices that want to keep their...

Details Behind the Body’s Response to Stress Revealed

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Summary: Study reveals how key proteins regulate the brain’s response to stress in the hippocampus.Source: McLean HospitalThe biological mechanisms behind stress-related psychiatric conditions, including major depressive...

Caitlyn’s PPPD Experience – Persistent Postural-Perception Dizziness

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I’m a 38 y/o professor of psychology with a focus on emotion. Which means I care a lot about scientific proof and a do a lot...

Childhood Disadvantage Affects Brain Connectivity

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Summary: Functional connectivity was reduced within and between several brain networks in children raised in disadvantaged neighborhoods. Researchers say a positive home and school environment can...

Migraine-Diet Connection: Dietary Triggers and Interventions for Migraine Management

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Dietary intake may precipitate migraine attacks, with up to 60% of patients reporting exacerbations following consumption of specific foods and beverages. Chocolate, coffee, cheese, and alcohol...

Co-Use of Alcohol and Cannabis and Its Effect on Mood, Subjective Experience

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The use of cannabis affected mood and subjective experience, alcohol impaired cognition and affected psychomotor performance, and the co-use of cannabis and alcohol was at most,...

AAN Calls for More Guidance for Aducanumab Use in Alzheimer Disease

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The safe prescription of aducanumab, an amyloid-β–directed human immunoglobulin G1 (IgG1) monoclonal antibody, in patients with symptomatic Alzheimer disease (AD) will require a substantial investment in...

Simulated Human Eye Movement Aims to Train Metaverse Platforms

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Summary: EyeSyn, a newly developed “virtual eye” that simulates how humans look at the world accurately enough for the development of new augmented reality programs, can...

The Effect of Physical Activity on Perceived Fatigue in Relapsing-Remitting MS

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Moderate-intensity physical activity may reduce perceived physical and cognitive fatigue among patients with relapsing-remitting multiple sclerosis (RRMS), according to research presented at the 2021 Annual Meeting...

Seven Tips about Depression, Anxiety Relief, Panic Attack

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By: Dr. Ellen Edgar  -  no responses  -  Anxiety Disorder, Depression, Depression, Anxiety Disorder, & Panic Attack, Neurological BlogAt present, the world is seeing a sharp rise in the number...

Treating Parkinson’s with Physical Therapy

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Parkinson’s physical therapy exercises improve balance, coordination, strength By Karen Hales, Neurology Solutions Contributing Writer Parkinson’s Disease (PD) has a wide range of symptoms...

New Neuropsychiatric Risks Among COVID-19 Patients Tied to Disease Severity

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Neuropsychiatric sequelae after severe COVID-19 was similar to the sequelae following other severe acute respiratory infections (SARIs), according to study findings published in JAMA Psychiatry. Data from...

Signals From Muscle Protect From Dementia

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Summary: Mimicking a muscular stress system can provide neuroprotection against aging in both the brain and retina. The signal helps prevent the buildup of misfolded protein...

HIPAA Needs to Keep Up With Information Technology

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Major updates with the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule are expected in the coming months, and many stakeholders are hoping for some...

Latin Dance May Be a Step Toward Better Working Memory for Older Latinos

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Summary: Latinos aged 55 and older who participated in Latin dance classes for eight months showed significant improvement in working memory over their peers who did...

Supernumerary Virtual Robotic Arms Can Feel Like Part of Our Body

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Summary: Researchers have developed a virtual robotic arm that can be controlled by a person’s feet in a virtual environment to provide an “extra” limb. After...

New Findings on Neuronal Activities in the Sensorimotor Cortex

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Summary: New findings about neural activity in the sensorimotor cortex may aid in the development of neuroprosthetics to help compensate for neuronal dysfunctions.Source: University of FreiburgAn...

Brain Regions Vulnerable to Disease May Lack Adequate Energy From Blood Supply

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Summary: Researchers say brain areas associated with neurodegenerative diseases tend to have less dense vascular networks which supply the brain with energy via the blood. The...

CBT, Contingency Management for Smoking Cessation in Adults With Obesity

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Among adults with a body mass index (BMI) of at least 25 who want to quit smoking but worry about weight gain after quitting, offering interventions...

Functional Movement Disorders And Deep Brain Stimulation: A Multi-center Study

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Congratulations to Drs. Okun, Almeida, and Deeb on the publicaiton of Functional Movement Disorders And Deep Brain Stimulation: A Multi-center Study,” in the October 30th issue...

Scientists Turn to EEG Data to Discover Just How COVID-19 Affects the Brain

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More than a third of patients with severe COVID-19 end up with neurological complications, including encephalopathy, stroke, and seizures. That is clear.What is not so clear...

Most Patients With Traumatic Brain Injury Regain Consciousness in Rehabilitation

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Patients with traumatic brain injury (TBI) often experience an initial disorder of consciousness (DOC) that persists after acute care, but most of these patients recover consciousness...

Control Hub for Skin Inflammation Discovered

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Summary: UV light from sunbathing and mosquito-borne diseases activate NLRP1 through p38, triggering skin inflammation.Source: University of BonnAs the largest organ of the human body, the...

STR1VE-EU Trial Shows Efficacy of Onasemnogene Abeparvovec in Spinal Muscular Atrophy

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Onasemnogene abeparvovec gene replacement therapy effectively helped infants with symptomatic spinal muscular atrophy type 1 (SMA1) achieve at least one episode of independent sitting in a...

The 60 faces of multiple sclerosis – The Neurology Lounge

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Multiple sclerosis (MS) dominates neurological practice in many parts of the world. This is no doubt because it is a common disorder which favours the young.The...

UF Health neurosurgeon awarded $38 million grant to lead national stroke prevention trial

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https://www.youtube.com/watch?v=8SW994tMaYY The National Institutes of Health on Tuesday awarded a $38 million, five-year grant to Brian Hoh, M.D., M.B.A., the University of Florida’s chair of neurosurgery, to...

MAMS Adaptive Trial Shows Promise for Future Progressive MS Treatments

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Clinical trials have produced remarkable strides in the treatment of multiple sclerosis (MS) in recent decades, especially for patients with the relapsing-remitting form of the disease....

Autism-Linked Gene Found to Shape Nerve Connections

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Summary: The autism-linked Gabrb3 gene appears to shape the formation of both normal and atypical neural connections in the brain.Source: Cornell UniversityA gene linked to autism...

SARS-CoV-2 Severity, Outcomes Linked to Age and Multiple Sclerosis Subtype

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Patients with multiple sclerosis (MS) and SARS-CoV-2 were at increased risk for severe disease and mortality if they were of advanced age and had progressive MS,...

Remote Ischemic Post-Conditioning With IVT May Improve Acute Ischemic Stroke Recovery

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Repeated remote ischemic post-conditioning (RIPC) combined with intravenous thrombolysis (IVT) can promote nerve function recovery and improve prognosis in patients with acute ischemic stroke, according to...

Spinal Cord Gray Matter Atrophy in Post-Polio Syndrome Tied to Functional Decline

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Spinal cord gray matter (SCGM) that correlated with muscle strength in post-polio syndrome (PPS) is associated with PPS-related functional decline, according to a study published in...

Have You Considered Scuba Therapy for Your Patients?

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For some patients suffering with neurological and physical disabilities, a potentially life-changing therapy can’t be found in a doctor’s office.Instead, TBI, cerebral palsy, MS, and Parkinson’s...

Fibrinogen in Acute Posttraumatic Hypofibrinogenemia in Severe Brain Injury

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Among patients with severe isolated head injury and acute posttraumatic hypofibrinogenemia, treatment with fibrinogen led to a higher Glasgow coma scale (GCS) score, better 90-day Glasgow...

Neanderthals Had the Capacity to Perceive and Produce Human Speech

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Summary: A new study reveals Neanderthals had the ability to perceive and produce human speech.Source: Binghamton UniversityNeandertals — the closest ancestor to modern humans — possessed...

Insights from A Parallel Distributed Processing Perspective » Department of Neurology » College of...

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Cerebral representations are encoded as patterns of activity involving billions of neurons. Parallel distributed processing (PDP) across these neuronal populations provides the basis for a number...

New study tests effectiveness of high-intensity exercise in slowing Parkinson’s symptoms » McKnight Brain...

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By Michelle Koidin Jaffee Dr. Malú Gámez TanseyThe University of Florida is collaborating on a new Phase 3 multisite clinical trial that will test the effectiveness of...

Childhood Emotional Trauma Linked to Heightened Multiple Sclerosis Risk Among Women

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Summary: Women who experienced childhood trauma had an increased risk of developing multiple sclerosis later in life. The evidence suggests childhood abuse and trauma can alter...

Understanding Memory Loss in Alzheimer’s Disease

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Summary: Findings reveal the accumulation of the synaptic protein neurexin may be a cause of memory loss associated with Alzheimer’s disease.Source: University of SevilleMembers of the...

One NDT Department’s Secret to Growth and Tech Satisfaction

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In the neurophysiology department at Houston Methodist Hospital, neurodiagnostic technicians tend to stick around. Amy Reynolds attributes her department’s continued growth and success to the dynamic...

Sustained Long-Term Efficacy of Cladribine in Multiple Sclerosis

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Cladribine shows durable efficacy for reducing frequency and severity of relapses in patients with relapsing-remitting multiple sclerosis, according to study results published in Multiple Sclerosis Journal. Treatment...

Many Patients With Multiple Sclerosis Harbor Misconceptions About Vaccinations

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Vaccine uptake was found to be decreased among the multiple sclerosis (MS) patient population, coupled with misconceptions about vaccine safety. These findings, from a cross-sectional study,...

Key Alzheimer’s Feature Eliminated in Animal Model

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Summary: Inhibiting the NHE6 gene abolished the formation of amyloid-beta plaques in mouse models of Alzheimer’s disease.Source: UT SouthwesternA study by UT Southwestern researchers finds that...

Optimal Blood Pressure Helps Our Brains Age Slower

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Summary: People whose blood pressure is elevated but still falls within the normal range are at increased risk of accelerated brain aging, researchers report.Source: ANUPeople with...

Antibody Response After Vaccination in People With MS Taking MAVENCLAD

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Physicians and patients alike question the impact and efficacy of vaccinations among individuals with multiple sclerosis (MS), especially in the context of the ongoing COVID-19 pandemic....

Why People Make Healthy Claims but Indulge in Unhealthy Behaviors

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Summary: When asked questions about sensitive behaviors, such as alcohol consumption or over-eating, people tend to respond in ways they consider socially correct while downplaying their...

When IONM Techs Make a Difference

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The efficacy and cost effectiveness of intraoperative neuromonitoring (IONM) can be difficult to determine.The perceived usefulness of IONM, according to Christopher Halford, the END (electroneurodiagnostic) program...

Experimental Vaccine Against Rheumatoid Arthritis Developed

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Summary: A new protein-based vaccine shows promise for improving bone quality and preventing rheumatoid arthritis.Source: University of ToledoResearchers at The University of Toledo have developed an...

Pregnant Women With Epilepsy More Likely to Have Medication Altered Following Seizure

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Changes to antiepileptic drug dosing were more frequent among pregnant women than nonpregnant women with epilepsy, according to study findings published in The New England Journal...

WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in...

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Congratulations Drs.  Zachary D. Simon,  Nikolaus R. McFarland, and  Malú Gámez Tansey on the publication of “WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and...

A Striking Difference Between Neurons of Humans and Other Mammals

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Summary: Human neurons have fewer ion channels compared to other animals. The reduced number of ion channels may have allowed the human brain to divert energy...

NCAM1: A Potential Biomarker for Charcot-Marie-Tooth Disease Progression

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Both neural cell adhesion molecule 1 (NCAM1) and growth differentiation factor 15 (GDF15) proteins have been identified as potential biomarkers of Charcot-Marie-Tooth (CMT) disease progression in...

Dementia patients are at greater risk for COVID-19, particularly African Americans and people with...

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New research is shedding light on how dementia can increase people’s risk for developing COVID-19, particularly among two groups: African Americans and...

Nonimmunogenic Staphylokinase Noninferior to Alteplase in Ischemic Stroke

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Nonimmunogenic staphylokinase was found to be noninferior to alteplase in patients with acute ischemic stroke when administered within 4.5 hours of onset of symptoms, according study...

New Mothers Could Help Protect Other Babies’ Brains

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Summary: Stem cells collected from the placentas of women who gave birth to healthy babies could reduce neuroinflammation and reduce brain injury in growth-restricted babies.Source: University...

Hope For Psychosis Sufferers – Neuroscience News

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Summary: A new model of schizophrenia opens the door to a better understanding of, and therapeutic options for brain dysfunction that is at the root of...

a crisis of access » Department of Neurology » College of Medicine » University...

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Congratulations Drs. Foote and Okun on the publication of “Deep brain stimulation for obsessive–compulsive disorder: a crisis of access,” in the July 15th issue of Nature...

A First Step in Standardizing Endpoints and Outcomes in Acute Migraine Trials

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Outcomes and endpoints used in acute migraine clinical trials vary significantly, but developing a core set of patient-centered outcomes and endpoints may improve individual trials and...

How the Brain Distinguishes Speech From Noise

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Summary: Study reports a pervasive neuromodulation system strongly influences sound processing in a key auditory region of the brain. Findings suggest acetylcholine may assist in the...

Addressing Sleep Disturbances of Parkinson Disease

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Among the various nonmotor symptoms affecting patients with Parkinson disease (PD), sleep disturbances are estimated to affect 40% to 90% of this population, and a study...

Adapted Ketogenic Diet and Neuroprotective Benefits in Multiple Sclerosis

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An adapted ketogenic diet (AKD) reduced serum neurofilament light chain (sNfL) levels at 6 months in patients with relapsing-remitting multiple sclerosis (MS), according to study findings...

UF neurologist named first diversity editor of JAMA Neurology » McKnight Brain Institute »...

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Ashley Rawls, M.D., has been appointed as the first-ever associate editor of diversity, equity and inclusion for the journal JAMA Neurology. In this role, Rawls, a clinical...

Early Coagulopathy Increases Mortality Risk in Children With TBI

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Early coagulopathy increases the risk of mortality and poor functional outcomes in both adults and children with traumatic brain injury (TBI), according to study results published...

Patients With Dystonia Have Increased Prevalence of Suicidal Behavior

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In a survey, 32.3% of patients with dystonia reported a lifetime history of suicidal ideations, which is a considerably higher rate of suicidal ideation than the...

Procedural Sequence Learning, Event File Binding Mechanisms in Tourette Syndrome

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In patients with Gilles de la Tourette syndrome (GTS), both procedural sequence learning and event file binding are enhanced and are potential cognitive mechanisms behind habitual...

Brain Abnormalities Seen in Epilepsy With Myoclonic Atonic Seizure Years Later

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Pediatric patients with epilepsy with myoclonic atonic seizures (EMAS) were found to have structural brain changes to the frontal lobes and cerebellum, according to study findings...

Unwanted Weight Gain or Weight Loss During the Pandemic? Blame Your Stress Hormones

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Summary: A recent study found 42% of participants gained, on average, 29 lb of unwanted weight during the pandemic, with people gaining 1.5 lb per month....

Atheists and Believers Both Have Moral Compasses, but With Key Differences

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Summary: Atheists are more likely to the morality of an action based on its consequences, while theists are more inclined to endorse moral values that promote...

10 perceptively catchy neuroscience titles – The Neurology Lounge

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The brain is arguably the most mysterious entity in the universe. It surprises us every time we believe we have got a handle on...

Study Maps Brain Regions Responsible For Intoxicating Effects of Alcohol

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Summary: The effects of intoxication, such as slurred speech and poor coordination, are a result of the breakdown of alcohol products in the brain and not...

Out-of-Hospital Cardiac Arrest: Sodium Serum Levels Tied to Neurological Outcomes

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Among patients who survived out-of-hospital cardiac arrest (OHCA), relatively high levels of serum sodium 24 hours after the return of spontaneous circulation (ROSC) were associated with...

PTSD With Depression May Significantly Increase Risk of Early Death in Women

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Summary: Women who experience PTSD and depression have a four-fold higher risk of early death from health problems, including cardiovascular disease and type 2 diabetes than...

Cells That Control Hunger Affect Brain Structure and Function

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Summary: AgRP neurons in the hypothalamus play a critical role in shaping the structure and function of the prefrontal cortex in mice. The findings shed light...

Development and Validation of Automated Magnetic Resonance Parkinsonism Index 2.0 to Distinguish Progressive Supranuclear...

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Congratulations Drs. David Vaillancourt and Nikolaus McFarland on the publication of “Development and Validation of Automated Magnetic Resonance Parkinsonism Index 2.0 to Distinguish Progressive Supranuclear Palsy-Parkinsonism...

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