Lifestyle Changes Lower BP in Patients With Resistant Hypertension

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A 4-month structured diet and exercise program significantly lowered blood pressure (BP) and body weight among patients with resistant hypertension (RH), according to study findings published...

How to Nurture Creativity in Your Kids

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Summary: Researches investigate the positive impact of nurturing creativity in children and evaluate methods for encouraging creativity.Source: UConnParents who want their kids to be more creative...

CSF Cell-Free DNA Superior to Cytology in Detecting Leptomeningeal Disease

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Cerebrospinal fluid (CSF) cell-free DNA (cfDNA) analysis was more sensitive and accurate than cytologic analysis for the purpose of diagnosing leptomeningeal disease (LMD), a serious complication...

Researchers seek to build confidence into AI for health care under NSF grant »...

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(From left) Drs. Ruogu Fang, Adolfo Ramirez-Zamora, and My T. ThaiA team of researchers led by principal investigator My T. Thai, Ph.D., a professor in the...

Fat Cells Found to Play a Central Role in Cognitive Decline and Neurodegeneration

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Summary: A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers...

The 30 most enduring neurological controversies – The Neurology Lounge

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The World Congress of Controversies in Neurology (CONy) has been held every year since 2007, and the most recent conference was held virtually in September 2021. The...

Impact of Gender Inequities in Infectious Diseases and Internal Medicine

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Although physicians might hope that there are no glass ceilings in medicine, recent evidence proves that to be untrue. In academic settings, women are under-represented in...

NF2 Symposium | The House Institute

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Register Today for the House Institute Foundation’s Virtual NF2 Symposium! This symposium is generously sponsored by Charles M. Seigel in heartfelt memory of NF2 patient, Paul Bruder...

How an Enriched Environment Fires up Our Synapses

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Summary: Post-genomic analysis of the regulation of synapses in a rodent hippocampus sheds new light on the interaction of proteins and lipids within the synaptic membrane.Source:...

Sonothrombolysis Improves Odds of Complete Recanalization in Acute Ischemic Stroke

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Ultrasound-enhanced thrombolysis, or sonothrombolysis, was associated with increased odds of complete recanalization vs intravenous thrombolysis in patients with acute ischemic stroke (AIS) with large vessel occlusions...

What Happens in Your Brain When You Make a Decision?

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Summary: Researchers examine the neuroscience behind why we make certain decisions when faced with multiple choices.Source: Lund UniversityYou rush into the supermarket; your mother-in-law is coming...

Levetiracetam Improves Cognition in Patients With Alzheimer Disease and Epilepsy

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Treatment with antiseizure drug levetiracetam was well-tolerated and associated with improvements in spatial memory and executive function tasks in patients with Alzheimer disease (AD) and epileptiform...

How the Brain Navigates Cities

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Summary: Researchers say the brain appears to be wired to calculate not the shortest path, but the “pointiest” path, facing us toward our destination as much...

Inosine Fails to Slow Early Parkinson Disease Progression in Phase 3 Trial

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Urate-elevating inosine treatment had no beneficial effect on the rate of clinical disease progression among patients with newly diagnosed Parkinson disease (PD), according to study results...

Spotlighting the Special Skills of EEG Techs who Work with Neonates

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Neurodiagnostic technologists play a “fundamental role” in the care of premature newborns, according to a new paper published in the journal Clinical Neurophysiology.Premature birth itself is...

Genes Play Key Role in Exercise Outcomes

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Summary: A new study reveals our genes play a key role in how our bodies respond to exercise. Researchers also identified specific genes that influence the...

Patients With Migraines Have Thinner Retinal Nerve Fiber Layers, Reduced Choroidal and Luminal Areas

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Researchers are exploring a number of vasogenic stimulus theories for the pathogenesis of migraine headache and, with the choroid being the most vascularized tissue of the...

AI Used to Reproduce Lost Picasso Nude

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Summary: A painting of a naked woman by Picasso has been hidden under one of his “Blue Period” works for almost a century. With the help...

Study Identifies New Genes Tied to Higher Risk for Parkinson Disease

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Several susceptibility genes for Parkinson disease (PD) were identified using a transcriptome wide association study (TWAS), and a phenome-wide association study for each single nucleotide polymorphism...

A Map of Mouse Brain Metabolism in Aging

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Summary: A new, freely available brain atlas reveals how brain metabolism changes throughout the life of mice.Source: UC DavisThe first atlas of metabolites in the mouse...

Understanding Alcohol Use and Dementia: From Diagnosis to Patient Education

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An estimated 50 million people currently have dementia, and projected prevalence rates for the years 2030 and 2050 are 82 million and 152 million, respectively, according...

Brain Activity Fluctuations May Hold the Keys to Psychiatric Treatment Efficacy

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Summary: Moment-to-moment fluctuations in brain activity over a three-minute period can reliably predict how receptive a person with social anxiety will be to cognitive behavioral therapy.Source:...

The 60 faces of multiple sclerosis – The Neurology Lounge

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Multiple sclerosis (MS) dominates neurological practice in many parts of the world. This is no doubt because it is a common disorder which favours the young.The...

Immunoprecipitation Mass-Spec Assays Superior in Detecting CSF and PET Amyloid Abnormality

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Plasma amyloid-beta (Aβ)42/40 quantified with particular mass spectrometry (MS)–based methods identified patients with abnormal brain Aβ burden more accurately than immunoassay-based Aβ42/40 measures, according to a...

Tackling the Replication Crisis in Neuroscience

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Summary: The European Quality in Preclinical Data announces the completion of their IMI project. The project provides a state of the art, learning, and fit-for-purpose system...

Oral Levosimendan Not Superior to Placebo for Respiratory Function in ALS

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Levosimendan, a calcium sensitizer, was not superior to placebo for maintaining respiratory function in patients with amyotrophic lateral sclerosis (ALS), according to study findings published in...

White Matter Integrity Disrupted in People With Alzheimer’s Gene Mutation

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Summary: Carriers of the ADAD Alzheimer’s-associated genetic mutation have lower structural connectivity in the frontoparietal control network.Source: RSNAThe structural integrity of the brain’s white matter as...

Worldwide Stroke Rates, Related Deaths Substantially Increased Since 1990

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From 1990 to 2019, the annual number of strokes and stroke-related deaths significantly increased worldwide, with high body mass index (BMI) representing the fastest-growing risk factor...

Neurology department focuses on diversity initiatives

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Rawls said through one recent community outreach project, a grant from the Parkinson’s Foundation allowed faculty to visit African-American churches in Gainesville to educate...

Mushroom Consumption May Lower Risk of Depression

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Summary: Regular consumption of mushrooms may reduce a person’s risk of developing depression, a new study reports.Source: Penn StateMushrooms have been making headlines due to their...

Optimal Blood Pressure Helps Our Brains Age Slower

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Summary: People whose blood pressure is elevated but still falls within the normal range are at increased risk of accelerated brain aging, researchers report.Source: ANUPeople with...

New Position Statement on MRI-Guided Laser Induced Thermotherapy for Epilepsy

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The American Society for Stereotactic and Functional Neurosurgery released a position statement on the recommended use of MRI-guided laser interstitial therapy (MRgLITT) as first-line surgical therapy...

Charting Hidden Territory of the Human Brain

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Summary: A new, non-invasive neuroimaging technique allowed researchers to investigate the visual sensory thalamus, a brain area associated with visual difficulties in dyslexia and other disorders.Source:...

T-Cell and Humoral Response to SARS-CoV-2 Vaccine in Patients With MS on Ocrelizumab

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Among patients with multiple sclerosis (MS) treated with ocrelizumab, vaccine-specific T-cell response was preserved, but humoral response was reduced compared with healthy individuals, according to study...

Clean Air Matters for a Healthy Brain

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Summary: Recent studies have linked air pollution to increased risks for Alzheimer’s disease and other health problems. A new study reports a reduction of atmospheric fine...

25 non-eponymous neurological disorders…and their pioneers – The Neurology Lounge

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Neurology is as much defined by its diseases as by the people who named them. In many cases, it is a no brainer that Benjamin...

Predictors of Deep Brain Stimulation Efficacy for Impulsive and Compulsive Behavior in PD

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Subthalamic nucleus-deep brain stimulation (STN-DBS) is associated with greater improvements in impulsive and compulsive behaviors (ICBs) in patients with Parkinson disease (PD) who have severe ICBs...

Q&A: Getting the Botox Dose Right for Cervical Dystonia

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Botulinum toxin type A injection is well established as the standard of care for cervical dystonia, but there is little evidence to recommend optimal treatment intervals...

Chemotherapy Drug Reverses Alzheimer’s Symptoms in Mice

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Summary: Axitinib, a chemotherapy drug that inhibits the growth of new blood vessels in the brain, improved memory and cognition in mouse models of Alzheimer’s disease.Source:...

Ocrelizumab Beneficial for Relapse Risk and Disability in Multiple Sclerosis

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Ocrelizumab, a humanized anti-CD20 immunoglobulin G (IgG) antibody, may effectively control the risk of relapse and disability worsening in patients with multiple sclerosis (MS), according to...

Natural Compound in Basil May Protect Against Alzheimer’s Disease

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Summary: Fenchol, a natural compound found in basil and other plans, appears to have a neuroprotective effect against Alzheimer’s disease. Fenchol reduces the formation of zombie...

Importance of Measuring Quality of Neurologic Care: Axon Registry Highlights

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Quality of neurologic care from the Axon Registry, a platform that helps its members measure, improve, and report clinical neurology quality measure, shows modest performance scores...

Experimental Vaccine Against Rheumatoid Arthritis Developed

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Summary: A new protein-based vaccine shows promise for improving bone quality and preventing rheumatoid arthritis.Source: University of ToledoResearchers at The University of Toledo have developed an...

Functional Inhibition of Occipital Nerve Likely Occurs Within Trigeminocervical Complex

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Greater occipital nerve (GON) block using lidocaine may aid in the treatment of various headache and facial pain syndromes, and according to study results published in...

Psychological Treatment Yields Strong, Lasting Relief for Chronic Pain Sufferers

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Summary: A four-week course of pain reprocessing therapy (PRT) provided up to 12 months of relief from pain for chronic pain sufferers. Additionally, the psychological treatment...

ADHD Persists Into Young Adulthood in 90% of Cases

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New findings challenge the belief that half of children with ADHD outgrow the condition by adulthood. Although patients may show intermittent periods of symptom remission, 90%...

The Neurobiology of Memes and Conspiracy Theories

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Summary: The propensity to believe in conspiracy theories may be a result of genetic determination, cognitive capacity, and affective reactions. Researchers found the representation of memes...

Does the Association of Fasting Blood Glucose With Stroke Risk Differ by Race and...

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There are sex differences in the association between impaired glucose metabolism and risk for ischemic stroke, as the strongest association between fasting blood glucose (FBG) and...

Early Accumulation of Tau in the Brain Predicts Memory Decline in Alzheimer’s Disease

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Summary: PET study finds early accumulation of the tau protein in the brain is a better predictor of Alzheimer’s associated memory decline than amyloid plaque accumulation...

Sleep Neurotherapeutics: Identifying the Challenges and Opportunities

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Sleep disorders are associated with a range of comorbidities and a substantial impairment in quality of life. Sleep disorders may result from or affect the progression...

Menopausal Hormone Therapy Not Linked to Increased Risk of Developing Dementia

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Summary: Despite previous claims, new research finds there is no link between menopausal women taking hormone replacement therapy (HRT) and an increased risk of developing dementia.Source:...

Strength Training May Benefit Gross Motor Function in Children With Cerebral Palsy

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Strength training is associated with improvements in muscle strength, gait speed, balance, and gross motor function in children and adolescents with spastic cerebral palsy, according to...

Q&A: Targeting the Right Muscles in Cervical Dystonia

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According to a 2020 Cochrane review, botulinum toxin type A injection is the “first-line therapy” for cervical dystonia, a painful movement disorder of the neck. Unfortunately,...

Study Identifies Protein Important for Motor Coordination and Exercise Performance

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Summary: Neurturin, a muscle-produced protein, improves muscular metabolism, motor coordination, and exercise performance in mouse models. The discovery could have implications for treating ALS and other...

Treatment Response to Zolpidem in Patients With Insomnia: The Importance of Priming

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Intermittent dosing of zolpidem with placebo after one month of full dose nightly zolpidem is an effective acute and extended treatment for patients with chronic insomnia...

Older Women More Likely to Report Depressive Symptoms Than Men

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Summary: Women over the age of 70 are more likely than men of the same age to report feeling symptoms of depression.Source: Simon Fraser UniversityDepression affects...

Dimethyl Fumarate Shows Favorable Long-Term Benefit-Risk Profile in MS

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Long-term treatment with dimethyl fumarate (DMF) demonstrated a favorable benefit-risk profile in patients with relapsing remitting multiple sclerosis (RRMS) up to 13 years in the ENDORDSE...

UF neurologist earns NIA Career Development Award » McKnight Brain Institute » University of...

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Dr. Bhavana PatelBy Todd Taylor Bhavana Patel, D.O., an assistant professor of neurology, has earned a K23 career development award from the National Institute on Aging, part...

Virtual Reality Affects Children Differently Than Adults

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Summary: Immersive virtual reality could disrupt a child’s default coordination strategy, researchers report.Source: EPFLWhile very little is known on the effects of immersive VR on adults,...

Higher HDL and Apolipoprotein A1 Levels Tied to Reduced ALS Risk

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Lipid metabolism is associated with the risk of developing amyotrophic lateral sclerosis (ALS), according to study results published in the Journal of Neurology, Neurosurgery, and Psychiatry. Premorbid...

Augmented Reality Helps Tackle Fear of Spiders

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Summary: A newly developed augmented reality smartphone app may help reduce the fear of spiders for arachnophobes.Source: University of BaselResearchers from the University of Basel have...

CAG Repeat Length Tied to Progression in Common Spinocerebellar Ataxias

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Among patients with spinocerebellar ataxias (SCA) type 1, 2, and 3, an autosomal dominantly inheritance, CAG length size was associated with faster disease progression, and had...

Children’s Dislike of Cauliflower and Broccoli Could Be Written in Their Microbiome

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Summary: Children whose saliva produced high amounts of sulfur volatiles disliked raw Brassica vegetables the most. The levels of sulfur volatiles were similar in parents and...

19 most unusual neurological symptoms and their elucidating checklists – The Neurology Lounge

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The brain, the principal playground of neurologists, is a complex organ. The more we learn about it, the more we have to unlearn our...

Nonimmunogenic Staphylokinase Noninferior to Alteplase in Ischemic Stroke

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Nonimmunogenic staphylokinase was found to be noninferior to alteplase in patients with acute ischemic stroke when administered within 4.5 hours of onset of symptoms, according study...

Increased Risk of Depression for Young People if Their Mothers Experienced Depression During or...

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Summary: By the age of 24, children born to mothers who suffered from depression during pregnancy or postpartum depression scored three points higher for depression scores...

Nosebleeds Lead to Graves Disease Diagnosis

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Ms J is a 14-year-old girl who presents to her pediatrician for increasing episodes of nosebleeds. The nosebleeds are occurring 3 to 4 times per week...

Does IONM Make Scoliosis Surgery Safer?

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Scoliosis surgery is safer than it has ever been, and many will say a big reason for this is the widespread adoption of intraoperative neuromonitoring (IONM)....

UF researchers on quest to understand, prevent and treat Alzheimer’s disease – News

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Welcome to From Florida, a podcast where you’ll learn how minds are connecting, great ideas are colliding and groundbreaking innovations become a reality because of the...

Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression

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Summary: Two new intranasal drugs slow inflammation and stop the spread of alpha-synuclein in mouse models of Parkinson’s disease. The drug also improved gait and balance...

Ecopipam Shows Promise in Tic Reduction in Children With Tourette Syndrome

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The following article is part of conference coverage from the International Congress of Parkinson’s Disease and Movement Disorders (MDS) Virtual Annual Meeting. Neurology Advisor’s staff will...

A pilot functional MRI study » Department of Neurology » College of Medicine »...

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Congratulations to Dr. Brian Coffey on the publication of “Reemergence of the language network during recovery from severe traumatic brain injury: A pilot functional MRI Study,”...

MIND Diet Linked to Better Cognitive Performance

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Summary: Study reports the MIND diet may help reduce a person’s risk of developing Alzheimer’s disease and help maintain cognition in older adults.Source: Rush University Medical...

Functional Outcomes Among Patients Treated With Fluoxetine After Stroke

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Compared with placebo, treatment with fluoxetine following an acute stroke had no effect on functional outcomes at 12 months; patients who received fluoxetine scored lower in...

Can Wireless EEG Help with Opioid Withdrawal?

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Opioid misuse is at an all-time high, with 2020 marking the most overdoses ever seen, according to a new report from the U.S. Centers for Disease...

Elevated Levels of Neurofilament Light and Heavy Chain as Diagnostic Biomarkers for ALS

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Cerebrospinal fluid (CSF) neurofilament light (NfL), CSF neurofilament heavy (NfH), and serum NfL are effective biomarkers in the differential diagnosis of patients with amyotrophic lateral sclerosis...

New Gene Therapy Pathway Could Protect Us From Cancer and Dementia

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Summary: A newly identified gene therapy pathway has the potential to protect us against dementia and cancer, researchers report.Source: University of SheffieldResearchers from the University of...

COVID-19 Vaccines Not Linked to Miscarriage in Surveillance Study

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Administration of the Pfizer-BioNTech and Moderna mRNA COVID-19 vaccines during pregnancy was not associated with an increased risk of miscarriage based on new surveillance data published...

New Technique Provides Insights Into the Evolution of the Brain

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Summary: H3 acetylation of basal neural precursor cells may have been an important factor in the evolution of the human neocortex.Source: RUBAs humans, we have a...

The 50 most fascinating neuroradiological pareidolias – The Neurology Lounge

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Humans have a tendency to see patterns and images where none exist. Many of these patterns were created (or evolved, depending on your view) as early...

Cognitive Decline in MS Linked to Ventral Attention Network

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Disruption of ventral attention network (VAN) functioning may trigger the switch from intact cognition to impairment in patients with multiple sclerosis (MS). These findings were published...

Converting Glioma Cells Into Neurons May Treat Glioblastoma

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Summary: Cellular reprogramming of glioma cells into neural cells may be a promising treatment for glioblastoma brain cancer.Source: Cactus CommunicationsGliomas are the most common primary brain...

Migraine Management: How to Treat Patients With Vascular Disease

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The frequency of vascular diseases, including arterial hypertension, coronary heart disease, and stroke have been associated with migraine. The presence of these vascular diseases in patients...

Complexity in Language Is Driven by the Needs of the Speakers

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Summary: When faced with having to distinguish similar pairs of meanings, speakers adjust their colexification preference to maintain efficient communication.Source: Estonia Research CouncilA recent study focusing...

Boxing Therapy May Reduce Risk for Falls in Patients With Parkinson Disease

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Boxing therapy may improve gait stability and reduce the risk for falls in patients with Parkinson disease (PD), according to study findings published in BMC Neurology. Motor...

UF, UF Health announce gift and new $75 million initiative to expand Norman Fixel...

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The University of Florida and UF Health on Tuesday announced an additional $25 million gift from the Lauren and Lee Fixel Family Foundation aimed at improving...

New Microscopy Technique Reveals Activity of One Million Neurons Across the Mouse Brain

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Summary: A new technique dubbed light beads microscopy allowed researchers to generate a vivid functional movie of the near-simultaneous activity of almost a million neurons in...

Case Reports: Adult-Onset Spinal Muscular Atrophy Linked to Variations in VRK1 Gene in Hispanic...

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Variations in the vaccine-related kinase 1 (VRK1) gene may result in adult-onset spinal muscular atrophy (SMA) without pontocerebellar atrophy in Hispanic adults, according to 2 case...

People Synchronize Heart Rates While Listening Attentively to Stories

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Summary: Heart rate synchronization occurs, even when people listen to a story alone, when paying attention to certain points of a story.Source: Cell PressPeople often unconsciously...

Direct to Angiography Suite Improves Functional Outcomes in LVO Stroke Shortly After Symptom Onset

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The direct transfer to angiography suite (DTAS) compared with direct transfer to computed tomography (DTCT) protocol is safe and leads to improved clinical outcomes in patients...

Do Alexa and Siri Make Kids Bossier?

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Summary: A new study shows how sophisticated social awareness in children can be in the transference of behavior.Source: University of WashingtonChatting with a robot is now...

What Is the Optimal Surgical Approach to Thymectomy in Myasthenia Gravis?

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Extended minimally invasive approaches to thymectomy are associated with rates of complete stable remission (CSR) similar to those achieved with extended transsternal approaches and may be...

The Relationship of Education and Income to Brain and Cognition Varies Across Groups of...

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Summary: Findings reveal the relationships between socioeconomic status, brain size, and cognition are established early in life.Source: University of OsloIn a study of more than 50.000...

Oral Atogepant Reduces Monthly Episodic Migraine Days

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Treatment with atogepant, an oral, small-molecule calcitonin gene–related peptide (CGRP) receptor antagonist, is safe and effective for migraine prophylaxis, according to full results of the phase...

How the Brain’s Motor System Can Support Vocabulary Learning

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Summary: A transcranial magnetic stimulation study revealed the motor cortex may play a role in translating foreign language words into one’s native tongue.Source: TUDThe motor cortex...

The 8 most parasitic infestations of the nervous system – The Neurology Lounge

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They gain access to our bodies by using any of our natural orifices, or they create their own. They burrow and nibble their way to the...

The Ongoing Challenge of Attracting and Retaining Health Care Providers

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The continuing COVID-19 pandemic is hastening the retirement of many health care providers. The United States now faces acute shortages of physicians, nurses, and medical assistants,...

New Vagus Nerve Stimulator Doubles Rate of Improvement After Stroke

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The U.S. Food and Drug Administration has just approved its first implantable vagus nerve stimulation device, the Vivistim System. The device has been shown to double...

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